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1

Correlation between Cytotoxicity and DNA Binding of Polypyridyl Ruthenium Complexes

Novakova, Olga, Kasparkova, Jana, Vrana, Oldrich, van Vliet, Paul M., Reedijk, Jan, Brabec, Viktor

Journal:

Year:

1995

Language:

english

File:

PDF, 2.72 MB

english, 1995

2

Biochemical Studies of the Thermal Effects on DNA Modifications by the Antitumor Cisplatin and Their Repair

Anna Halamikova, Oldrich Vrana, Jana Kasparkova, Viktor Brabec

Journal:

Year:

2007

Language:

english

File:

PDF, 538 KB

english, 2007

3

Platinum determination in cis-dichlorodiammineplatinum(II)-DNA complexes by differential pulse polarography

Oldřich Vrána, Viktor Brabec

Journal:

Analytical Biochemistry

Year:

1984

Language:

english

File:

PDF, 684 KB

english, 1984

4

mer-[Ru(terpy)Cl3] (terpy = 2,2′:6′,2″-terpyridine) shows biological activity, forms interstrand cross-links in DNA and binds two guanine derivatives in a trans configuration

Paul M. van Vliet, Sarinten M.S. Toekimin, Jaap G. Haasnoot, Jan Reedijk, Olga Nováková, Oldrich Vrána, Viktor Brabec

Journal:

Inorganica Chimica Acta

Year:

1995

Language:

english

File:

PDF, 752 KB

english, 1995

5

Electrochemical analysis of antitumour platinum drugs and their complexes with DNA

Oldřich Vrána, Viktor Brabec

Journal:

Journal of Electroanalytical Chemistry and Interfacial Electrochemistry

Year:

1988

Language:

english

File:

PDF, 1.35 MB

english, 1988

6

Prevention of ventricular fibrillation at the onset of myocardial infarction. Randomized trial with self-administered electrostabilizing drugs

Zdenêk Fejfar, Milan Vrána, Oldřich Horák

Journal:

Year:

1993

Language:

english

File:

PDF, 141 KB

english, 1993

7

The effect of platinum derivatives on interfacial properties of DNA

Dana Kašparová, Oldřich Vrána, Vladimír Kleinwächter, Viktor Brabec

Journal:

Biophysical Chemistry

Year:

1987

Language:

english

File:

PDF, 641 KB

english, 1987

8

Electrochemical analysis of antitumour platinum drugs and their complexes with DNA

Oldřich Vrána, Viktor Brabec

Journal:

Bioelectrochemistry and Bioenergetics

Year:

1988

Language:

english

File:

PDF, 1.05 MB

english, 1988

9

A comparison of DNA binding profiles of dinuclear platinum compounds with polyamine linkers and the trinuclear platinum phase II clinical agent BBR3464

Tracey D. McGregor, Alexander Hegmans, Jana Kašpárková, Kamila Neplechová, Olga Nováková, Hana Peňazová, Oldrich Vrána, Viktor Brabec, Nicholas Farrell

Journal:

JBIC Journal of Biological Inorganic Chemistry

Year:

2002

Language:

english

File:

PDF, 180 KB

english, 2002

10

Migration, wintering and breeding of a lesser spotted eagle (Aquila pomarina) from Slovakia tracked by satellite

Bernd-U. Meyburg, Christiane Meyburg, Tomáš Bělka, Oldrich Šreibr, Josef Vrana

Journal:

Journal of Ornithology

Year:

2004

Language:

english

File:

PDF, 227 KB

english, 2004

11

Effect of the geometry of the central coordination sphere in antitumor trinuclear platinum complexes on DNA binding

Jana Kasparkova, Oldrich Vrana, Nicholas Farrell, Viktor Brabec

Journal:

Journal of Inorganic Biochemistry

Year:

2004

Language:

english

File:

PDF, 332 KB

english, 2004

12

Biophysical studies of the modification of poly(rG) · poly(rC) by cisplatin. Relations to the biological activity of the complex

Viktor Brabec, Oldrich Vrána, Galina A. Platonova, Elvira M. Kogan, Nina S. Sidorova

Journal:

Chemico-Biological Interactions

Year:

1991

Language:

english

File:

PDF, 763 KB

english, 1991

13

Interaction of alkaline phosphatase with cytochrome c

Vladimír Dadák, Oldřich Vrána, Olga Nováková, Marián Antalík

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1996

Language:

english

File:

PDF, 758 KB

english, 1996

14

Conversion of DNA adducts of antitumour cis-diamminedichloroplatinum (II). Immunochemical analysis

Oldrich Vrána, Valentina I. Kiseleva, Alexander M. Poverenny, Viktor Brabec

Journal:

European Journal of Pharmacology: Molecular Pharmacology

Year:

1992

Language:

english

File:

PDF, 915 KB

english, 1992

15

Conformation and recognition of DNA modified by a new antitumor dinuclear PtII complex resistant to decomposition by sulfur nucleophiles

Lenka Zerzankova, Tereza Suchankova, Oldrich Vrana, Nicholas P. Farrell, Viktor Brabec, Jana Kasparkova

Journal:

Biochemical Pharmacology

Year:

2010

Language:

english

File:

PDF, 393 KB

english, 2010

16

Cytotoxicity, cellular uptake, glutathione and DNA interactions of an antitumor large-ring PtII chelate complex incorporating the cis-1,4-diaminocyclohexane carrier ligand

Jana Kasparkova, Tereza Suchankova, Anna Halamikova, Lenka Zerzankova, Oldrich Vrana, Nicola Margiotta, Giovanni Natile, Viktor Brabec

Journal:

Biochemical Pharmacology

Year:

2010

Language:

english

File:

PDF, 889 KB

english, 2010

17

Polyclonal antibodies elicited aganist trans-diamminedichloroplatinum(II)-modified DNA and their application in nonradioactive hybridization experiments

Viktor BRABEC, Oldrich VRANA, Valentina I. KISELEVA, Alexander M. POVERENNY

Journal:

Year:

1991

Language:

english

File:

PDF, 927 KB

english, 1991

18

DNA Interactions of Antitumor Platinum(IV) Complexes

Olga Nováková, Oldřich Vrána, Valentina I. Kiseleva, Viktor Brabec

Journal:

Year:

1995

Language:

english

File:

PDF, 1.07 MB

english, 1995

19

DNA Interactions of Bifunctional Dinuclear Platinum(II) Antitumor Agents

Renata Žaludová, Alena Žákovská, Jana Kašpárková, Zdenka Balcarová, Vladimír Kleinwächter, Oldřich Vrana, Nicholas Farrell, Viktor Brabec

Journal:

Year:

1997

Language:

english

File:

PDF, 1.24 MB

english, 1997

20

DNA Interactions of Monofunctional Organometallic Ruthenium(II) Antitumor Complexes in Cell-free Media†

Novakova, Olga, Chen, Haimei, Vrana, Oldrich, Rodger, Alison, Sadler, Peter J., Brabec, Viktor

Journal:

Year:

2003

Language:

english

File:

PDF, 180 KB

english, 2003

21

Polarographic Determination of Subnanogram Quantities of Free Platinum in Reaction Mixture with Dna

Kim, Sung D., Vrána, Oldřich, Kleinwächter, Vladimír, Niki, Katsumi, Brabec, Viktor

Journal:

Analytical Letters

Year:

1990

Language:

english

File:

PDF, 472 KB

english, 1990

22

Amide-Based Prodrugs of Spermidine-Bridged Dinuclear Platinum. Synthesis, DNA Binding, and Biological Activity

Hegmans, Alexander, Kasparkova, Jana, Vrana, Oldrich, Kelland, Lloyd R., Brabec, Viktor, Farrell, Nicholas P.

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 448 KB

english, 2008

23

Raman spectroscopy of DNA modified by intrastrand cross-links of antitumor cisplatin

Oldřich Vrána, Vlastimil Mašek, Viktor Dražan, Viktor Brabec

Journal:

Journal of Structural Biology

Year:

2007

Language:

english

File:

PDF, 265 KB

english, 2007

24

Cytochrome c forms complexes and is partly reduced at interaction with GPI-anchored alkaline phosphatase

Vladimı́r Dadák, Oldrich Janiczek, Oldrich Vrána

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

2002

Language:

english

File:

PDF, 394 KB

english, 2002

25

Structural Characterization, DNA Interactions, and Cytotoxicity of New Transplatin Analogues Containing One Aliphatic and One Planar Heterocyclic Amine Ligand

Ramos-Lima, Francisco J., Vrána, Oldřich, Quiroga, Adoración G., Navarro-Ranninger, Carmen, Halámiková, Anna, Rybníčková, Hana, Hejmalová, Lenka, Brabec, Viktor

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 322 KB

english, 2006

26

Organometallic Half-Sandwich Iridium Anticancer Complexes

Liu, Zhe, Habtemariam, Abraha, Pizarro, Ana M., Fletcher, Sally A., Kisova, Anna, Vrana, Oldrich, Salassa, Luca, Bruijnincx, Pieter C. A., Clarkson, Guy J., Brabec, Viktor, Sadler, Peter J.

Journal:

Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 4.06 MB

english, 2011

27

Unique DNA Binding Mode of Antitumor Trinuclear Tridentate Platinum(II) Compound

Olivova, Radana, Kasparkova, Jana, Vrana, Oldrich, Vojtiskova, Marie, Suchankova, Tereza, Novakova, Olga, He, Weijiang, Guo, Zijian, Brabec, Viktor

Journal:

Molecular Pharmaceutics

Year:

2011

Language:

english

File:

PDF, 765 KB

english, 2011

28

Conformation and recognition of DNA damaged by antitumor cis-dichlorido platinum(II) complex of CDK inhibitor bohemine

Novakova, Olga, Liskova, Barbora, Vystrcilova, Jana, Suchankova, Tereza, Vrana, Oldrich, Starha, Pavel, Travnicek, Zdenek, Brabec, Viktor

Journal:

European Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 846 KB

english, 2014

29

Mechanistic insights into toxic effects of a benzotriazolate-bridged dinuclear platinum(II) compound in tumor cells

Olivova, Radana, Stepankova, Jana, Muchova, Tereza, Novohradsky, Vojtech, Novakova, Olga, Vrana, Oldrich, Kasparkova, Jana, Brabec, Viktor

Journal:

Inorganica Chimica Acta

Year:

2012

Language:

english

File:

PDF, 394 KB

english, 2012

30

Antitumor platinum(IV) derivatives of oxaliplatin with axial valproato ligands

Novohradsky, Vojtech, Zerzankova, Lenka, Stepankova, Jana, Vrana, Oldrich, Raveendran, Raji, Gibson, Dan, Kasparkova, Jana, Brabec, Viktor

Journal:

Journal of Inorganic Biochemistry

Year:

2014

Language:

english

File:

PDF, 625 KB

english, 2014

31

Synthesis, Biophysical Studies, and Antiproliferative Activity of Platinum(II) Complexes Having 1,2-Bis(aminomethyl)carbobicyclic Ligands

de Mier-Vinué, Jordi, Gay, Marina, Montaña, Ángel M., Sáez, Rosa-Isabel, Moreno, Virtudes, Kasparkova, Jana, Vrana, Oldrich, Heringova, Pavla, Brabec, Viktor, Boccarelli, Angela, Coluccia, Mauro, Nati

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 513 KB

english, 2008

32

Different Features of the DNA Binding Mode of Antitumor cis -Amminedichlorido(cyclohexylamine)platinum(II) (JM118) and Cisplatin in Vitro

Kostrhunova, Hana, Vrana, Oldrich, Suchankova, Tereza, Gibson, Dan, Kasparkova, Jana, Brabec, Viktor

Journal:

Chemical Research in Toxicology

Year:

2010

Language:

english

File:

PDF, 3.36 MB

english, 2010

33

l -Methionine Inhibits Reaction of DNA with Anticancer cis- Diamminedichloroplatinum(II) †

Vrana, Oldrich, Brabec, Viktor

Journal:

Year:

2002

Language:

english

File:

PDF, 68 KB

english, 2002

34

Effect of Geometric Isomerism in Dinuclear Platinum Antitumor Complexes on DNA Interstrand Cross-Linking †

Kašpárková, Jana, Nováková, Olga, Vrána, Oldřich, Farrell, Nicholas, Brabec, Viktor

Journal:

Year:

1999

Language:

english

File:

PDF, 122 KB

english, 1999

35

The Effect of Combined Treatment with Platinum Complexes and Ionizing Radiation on DNA in Vitro

Vrána, Oldřich, Brabec, Viktor

Journal:

International Journal of Radiation Biology

Year:

1986

Language:

english

File:

PDF, 819 KB

english, 1986

36

New insights into the molecular and epigenetic effects of antitumor Pt(IV)-valproic acid conjugates in human ovarian cancer cells

Novohradsky, Vojtech, Zerzankova, Lenka, Stepankova, Jana, Vrana, Oldrich, Raveendran, Raji, Gibson, Dan, Kasparkova, Jana, Brabec, Viktor

Journal:

Biochemical Pharmacology

Year:

2015

Language:

english

File:

PDF, 1003 KB

english, 2015

37

Biophysical analysis of DNA modified by 1,2-diaminocyclohexane platinum(II) complexes

Boudný, Vladimir, Vrána, Oldrich, Gaucheron, Frederic, Kleinwachter, Vladimir, Leng, Marc, Brabec, Viktor

Journal:

Nucleic Acids Research

Year:

1992

Language:

english

File:

PDF, 2.46 MB

english, 1992

38

The Study of Naphthoquinones and Their Complexes with DNA by Using Raman Spectroscopy and Surface Enhanced Raman Spectroscopy: New Insight into Interactions of DNA with Plant Secondary Metabolites

Vaverkova, Veronika, Vrana, Oldrich, Adam, Vojtech, Pekarek, Tomas, Jampilek, Josef, Babula, Petr

Journal:

BioMed Research International

Year:

2014

Language:

english

File:

PDF, 2.45 MB

english, 2014

39

Potentiation of mitochondrial dysfunction in tumor cells by conjugates of metabolic modulator dichloroacetate with a Pt(IV) derivative of oxaliplatin

Zajac, Juraj, Kostrhunova, Hana, Novohradsky, Vojtech, Vrana, Oldrich, Raveendran, Raji, Gibson, Dan, Kasparkova, Jana, Brabec, Viktor

Journal:

Journal of Inorganic Biochemistry

Year:

2016

Language:

english

File:

PDF, 675 KB

english, 2016

40

Comment on “Delivering a photosensitive transplatin prodrug to overcome cisplatin drug resistance” by H. Song, W. Li, R. Qi, L. Yan, X. Jing, M. Zheng and H. Xiao, Chem. Commun., 2015, 51, 11493

Brabec, Viktor, Vrana, Oldrich, Novakova, Olga, Kasparkova, Jana

Journal:

Chemical Communications

Year:

2016

Language:

english

File:

PDF, 620 KB

english, 2016

41

Diet of the Lesser Spotted Eagle (Aquila pomarina) in Slovakia

Dravecký, Miroslav, Danko, Štefan, Obuch, Ján, Kicko, Ján, Maderič, Boris, Karaska, Dušan, Vrána, Josef, Šreibr, Oldřich, Šotnár, Karol, Vrlík, Peter, Bohačík, Ladislav

Journal:

Slovak Raptor Journal

Year:

2008

File:

PDF, 2.55 MB

2008

42

Internalization of Ineffective Platinum Complex in Nanocapsules Renders It Cytotoxic

Vrana, Oldrich, Novohradsky, Vojtech, Medrikova, Zdenka, Burdikova, Jana, Stuchlikova, Olga, Kasparkova, Jana, Brabec, Viktor

Journal:

Chemistry - A European Journal

Year:

2016

Language:

english

File:

PDF, 1.16 MB

english, 2016

43

Enhancing Tumor Cell Response to Chemotherapy through the Targeted Delivery of Platinum Drugs Mediated by Highly Stable, Multifunctional Carboxymethylcellulose-Coated Magnetic Nanoparticles

Medříková, Zdenka, Novohradsky, Vojtech, Zajac, Juraj, Vrána, Oldřich, Kasparkova, Jana, Bakandritsos, Aristides, Petr, Martin, Zbořil, Radek, Brabec, Viktor

Journal:

Chemistry - A European Journal

Year:

2016

Language:

english

File:

PDF, 1.03 MB

english, 2016

44

DNA Interactions of New Antitumor Aminophosphine Platinum(II) Complexes

Neplechová, Kamila, Kašpárková, Jana, Vrána, Oldřich, Nováková, Olga, Habtemariam, Abraha, Watchman, Beth, Sadler, Peter J., Brabec, Viktor

Journal:

Molecular Pharmacology

Year:

1999

Language:

english

File:

PDF, 265 KB

english, 1999

45

DNA Modifications by Antitumor trans -[PtCl 2 ( E -Iminoether) 2 ]

Žaludová, Renata, Žákovská, Alena, Kašpárkova, Jana, Balcarová, Zdenka, Vrána, Oldřich, Coluccia, Mauro, Natile, Giovanni, Brabec, Viktor

Journal:

Molecular Pharmacology

Year:

1997

Language:

english

File:

PDF, 483 KB

english, 1997

46

Correction: Simultaneous delivery of olaparib and carboplatin in PEGylated liposomes imparts this drug combination hypersensitivity and selectivity for breast tumor cells

Novohradsky, Vojtech, Zajac, Juraj, Vrana, Oldrich, Kasparkova, Jana, Brabec, Viktor

Journal:

Year:

2018

Language:

english

File:

PDF, 670 KB

english, 2018

47

Simultaneous delivery of olaparib and carboplatin in PEGylated liposomes imparts this drug combination hypersensitivity and selectivity for breast tumor cells

Novohradsky, Vojtech, Zajac, Juraj, Vrana, Oldrich, Kasparkova, Jana, Brabec, Viktor

Journal:

Year:

2018

Language:

english

File:

PDF, 7.47 MB

english, 2018